Program
| 09.00 – 10.30 h / Room Tokio Workshop 19 Viral Persistence and Immune Evasion |
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| Chair: | Ulrich Koszinowski, Bracha Rager | |
| Keynote Lecture: | Antonio Alcami: | |
| 09.00 - 09.30 h | Viral mimicry of cytokine receptors: contribution to pathogenesis and immune modulation | |
| 09.30 - 10.30 h | Oral presentations: | |
| Cytomegalovirus evasion of innate immunity by subversion of the NKR-P1B:Ocil/Clr-b missing-self axis * Sebastian Voigt (1), Aruz Mesci (2), Jakob Ettinger (1), Jason Fine (2), Peter Chen (2), Wayne Chou (2), James Carlyle (2) (1) Robert Koch Institute, Division of Viral Infections, Berlin, Germany; (2) University of Toronto, Department of Immunology, Toronto, Canada |
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| Selective Inhibition of host FcγR activation through Herpesviral Fcγ Receptors * Eugenia Corrales-Aguilar (1), Henrike C. Reinhard (1), Albert Zimmermann (1), David C. Johnson (2), Ofer Mandelboim (3), Hartmut Hengel (1) (1) Virology, Düsseldorf, Germany; (2) OHSU, Portland, USA; (3) Jerusalem, Israel |
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| Polyomavirus JC (JCV) with rearranged noncoding control region (rr-NCCR) are found in CSF, but not in urine and increase early gene expression * Rainer Gosert (1), Adrian Egli (1), Sohrab Bodaghi (1), Nina Khanna (1), Nicolas Müller (1), Hans H. Hirsch (1) (1) Medical Microbiology, Basel, Switzerland |
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| Borna disease virus with terminally truncated genome can retrieve missing genetic information * A. Martin (1), J. Tadewaldt (1), P. Staeheli (1), U. Schneider (1) (1) University of Freiburg, Dep. Virology, Freiburg, Germany |
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| 09.00 – 10.30 h / Room Istanbul Workshop 20 Antivirals and Resistance |
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| Chair: | Bruno Lina, Elisabeth Puchhammer-Stöckl | |
| Keynote Lecture: | John M. Coffin: | |
| 09.00 - 09.30 h | Antiviral drugs and the HIV-host relationship: Resistance and Persistence | |
| 09.30 - 10.30 h | Oral presentations: | |
| Peptide-mediated interference with the influenza A virus polymerase * Alexander Ghanem (1), Daniel Mayer (1), Geoffrey Chase (1), Ronald Frank (2), Georg Kochs (1), Adolfo Garcia-Sastre (3), Martin Schwemmle (1) (1) University of Freiburg, Department of Virology, Freiburg, Germany; (2) HCI, Braunschweig, Germany; (3) MSSM, NY, USA |
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| Filoviral Receptor-Binding Domains are Promising Subunit Vaccine Candidates * Jens H. Kuhn (1), Kelly L. Warfield (2), Sheli R. Radoshitzky (1), Dana Swenson (2), Gene G. Olinger (2), Sina Bavari (2), Michael Farzan (1), M. Javad Aman (2) (1) New England Primate Research Center, Harvard Medical School, Southborough, MA, USA; (2) USAMRIID, Ft. Detrick, Frederick, MD, USA |
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| Chimeric TCR for antiviral therapy * Florian Full (1), Gabriel Götz (2), Manfred Lehner (2), Michael Mach (1), Wolfgang Holter (2), Armin Ensser (1) (1) Virologisches Institut, Universitätsklinikum Erlangen, Erlangen, Germany; (2) Klinik für Kinder und Jugendliche, Universitätsklinikum Erlangen, Erlangen, Germany |
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| HIV cleavage site mutations and protease-inhibitor resistance * Jens Verheyen (1), Elena Litau (1), Tobias Sing (2), Herbert Pfister (1), Rolf Kaiser (1) (1) Institute of Virology, University of Cologne, Cologne, Germany; (2) Max Planck Institute for Informatics, Saarbrücken, Germany |
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| 09.00 – 10.30 h / Room Shanghai Workshop 21 Herpesviruses / DNA Viruses II |
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| Chair: | Giuseppe Gerna, Nikolaus Müller-Lantzsch | |
| Keynote Lecture: | Gabriella Campadelli-Fiume: | |
| 09.00 - 09.30 h | Herpes simplex virus, the entry mechanism of a complex virus | |
| 09.30 - 10.30 h | Oral presentations: | |
| Unravelling the structure function relationship of the HCMV encoded Fcγ-receptors * Henrike Reinhard (1), Elizabeth R. Sprague (2), Albert Zimmermann (1), Pamela J. Bjorkman (2), Hartmut Hengel (1) (1) Virology, Duesseldorf, Germany; (2) California Inst. of Technology, Pasadena, USA |
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| CMV-adrenalitis in patients with HIV infection * Sven Grützmeier (1), Eric Sandström (1), Anneka Ehrnst (2), Inger Nennesmo (3) (1) Karolinska University Hospital, Department of Infectious Diseases, Stockholm, Sweden; (2) MTC, Karolinska Institute, Stockholm, Sweden; (3) Karolinska University Hospital, Department of Pathology, Huddinge, Sweden |
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| MCMV retargets costimulatory molecules of the immune system by enhancing clathrin mediated endocytosis * Pen Kay-Jackson (1), Andrea Loewendorf (2), Martin Messerle (1) (1) Medical School, Virology, Hannover, Germany; (2) La Jolla Institute for Allergy and Immunology, San Diego, USA |
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| New plasmacytoid dendritic cell (PDC) surface receptors indicate novel types of cellular interactions in the defense of herpesviral infections * Philipp Schuster (1), Norbert Donhauser (1), Nico Kittan (1), Sabrina Haupt (1), Barbara Schmidt (1) (1) Institute of Virology, University of Erlangen-Nürnberg, Germany |
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10.30 - 11.00 h |
COFFEE BREAK |
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| 11.00 – 13.00 h / Room Tokio Workshop 22 Viral Oncology |
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| Chair: | Thomas Schulz, Jan Svoboda | |
| Keynote Lecture: | Kuan-Teh Jeang: | |
| 11.00 - 11.30 h | HTLV-1 and transformation: multisteps to genetic damage | |
| 11.30 - 13.00 h | Oral presentations: | |
| Physical and Functional interactions of human endogenous retrovirus k proteins Np9 and Rec with the Promyelocytic Leukemia Zinc Finger(PLZF)protein * M. Denne (1), M. Sauter (1), V. Armbruester (1), JD. Licht (2), K. Roemer (1), N. Mueller-Lantzsch (1) (1) Inst. of Virology, Homburg, Germany; (2) Div. of Oncology, Chicago, USA |
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| Reduced UV-induced apoptosis by specific papillomaviruses associated with skin cancer Linda Struijk (1), Els van der Meijden (1), Frank de Gruijl (2), * Mariet Feltkamp (1) (1) Leiden University Medical Center, Medical Microbiology, Leiden, The Netherlands; (2) LUMC, Dermatology, Leiden, The Netherlands |
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| T-cellular signaling pathways influenced by Herpesvirus saimiri oncoprotein StpC * Anja Glanz (1), Jens-Christian Albrecht (1), Stefanie Heinemann (1), Bernhard Fleckenstein (1), Noah Isakov (2), Brigitte Biesinger (1) (1) Virologisches Institut, Universitätsklinikum, Erlangen, Germany; (2) Ben Gurion University of the Negev, Beer Sheva, Israel |
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| The viral interferon regulatory factor-3 (K10.5, LANA-2) is required for the proliferation of infected primary effusion lymphoma cells and counteracts cellular IRF-5 * Effi Wies (1), Alexander Hahn (1), Nadine Rohland (1), Angela Holzer (1), Bernhard Fleckenstein (1), Frank Neipel (1) (1) Universität Erlangen, Virologisches Institut, Erlangen, Germany |
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| Systematic Analysis of Combination Effects of HHV-8 genes on NF-κB Activation A. Konrad (1), E. Wies (1), G, Sander (1), M. Thurau (1), E. Naschberger (1), S. Bauer (1), R. Leubert (1), T.F. Schulz (2), F. Neipel (1), * M. Stürzl (1) (1) Univ. of Erlangen, Erlangen, Germany; (2) Univ. of Hannover, Hannover, Germany |
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| Elevated expression of oncogenic microRNAs in HTLV-1 transformed T cells and ATL leukemia cells * Klemens Pichler (1), Claudine Pique (2), Ralph Grassmann (1) (1) Virology, University of Erlangen-Nürnberg, Erlangen, Germany; (2) Institute Cochin, Paris, France |
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| 11.00 – 13.00 h / Room Istanbul Workshop 23 Zoonoses |
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| Chair: | Åke Lundkvist, Ernst Peterhans | |
| Keynote Lecture: | Noël Tordo: | |
| 11.00 - 11.30 h | Bats and viruses | |
| 11.30 - 13.00 h | Oral presentations: | |
| Spread and evolution of HPAI H5N1 in poultry, humans and wild-birds in Subsaharan Africa C. Olinger (1), A. Owoade (2), A. Nasadi (3), M. Ducatez (1), Z. Tarnagda (4), M. Tahita (4), A. Sow (5), A. Osterhaus (6), J. Ouedraogo (4), R. Fouchier (6), * C. Muller (1) (1) Institute of Immunology, Luxembourg, Luxembourg; (2) Dept. Veterinary Medicine, Univ. Ibadan, Ibadan, Nigeria; (3) Ministry of Health, Abuja, Nigeria; (4) Institut de Recherche en Santé, Bobo-Dioulasso, Burkina Faso; (5) Laboratoire National de l'élevage, Ougadougou, Burkina Faso; (6) Dept. Virology, Erasmus Medical Center, Rotterdam, Netherlands |
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| Scrapie infection of PrP deficient cell line upon ectopic exression of mutant prion proteins Elke Maas (1), Markus Geissen (2), Martin Groschup (2), Romina Rost (1), Lars Gädtke (1), Takashi Onodera (3), Hermann Schätzl (1), * Ina Vorberg (1) (1) Technical University of Munich, Institute of Virology, Munich, Germany; (2) Friedrich-Loeffler-Institute, Institute for Novel and Emerging Infectious Diseases, Greifswald, Germany; (3) University of Tokyo, Department of Immunology, Tokyo, Japan |
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| Chikungunya fever in travellers returning from the Indian Ocean region * Marcus Panning (1), Klaus Grywna (1), Marjan van Esbroeck (2), Petra Emmerich (1), Christian Drosten (1) (1) Bernhard Nocht Institute for Tropical Medicine, Clinical Virology, Hamburg, Germany; (2) Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium |
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| A new primate animal model for orthopoxvirus infections * Marit Kramski (1), Kerstin Mätz-Rensing (2), Christiane Stahl-Hennig (2), Franz-Josef Kaup (2), Georg Pauli (1), Heinz Ellerbrok (1) (1) Robert Koch-Institut, ZBS1, Berlin, Germany; (2) German Primate Center, Göttingen, Germany |
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| Isolation of a new flavivirus from mosquitoes collected in the Tai National Park, Côte d’Ivoire * Sandra Junglen (1), Andreas Kurth (1), Fabian Leendertz (1), Georg Pauli (1), Heinz Ellerbrok (1) (1) Robert Koch-Institut, ZBS1, Berlin, Germany |
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| A novel Dobrava virus lineage carried by Apodemus ponticus (caucasian wood mouse) causes moderate/severe hemorrhagic fever with renal syndrome (HFRS) * Detlev H Kruger (1), Boris Klempa (1), Tamara Dzagurova (2), Yuliya Yunicheva (2), Vyacheslav Morozov (2), Nataliya Okulova (2), Evgeniy A. Tkachenko (2) (1) Charité Med.School, Inst. Virology, Berlin, Germany; (2) Russ.Acad.Med.Sci., Chumakov Inst. Poliomyelitis, Moscow, Russia |
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| 11.00 – 13.00 h / Room Shanghai Workshop 24 Hepatitis Viruses II (HCV) |
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| Chair: | Michael Nassal, Thomas Pietschmann | |
| Keynote Lecture: | Darius Moradpour: | |
| 11.00 - 11.30 h | New insights into the replication and pathogenesis of hepatitis C virus | |
| 11.30 - 13.00 h | Oral presentations: | |
| Different gene expression profile distinguish responders from non responders to HCV treatment * A. Almeida (1), J. Caetano (2), P. Santos (2), A. Martinho (2), C. Valente (3), B. Pais (3), C. Luxo (4) (1) C. Histocompatibilidade do Centro; Faculdade de Farmácia -UC, Coimbra, Portugal; (2) C. Histocompatibilidade do Centro, Coimbra, Portugal; (3) Centro Hospitalar de Coimbra, Coimbra, Portugal; (4) Faculdade de Farmácia UC, Coimbra, Portugal |
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| Domain III of hepatitis C virus non-structural protein 5A is essential for virus production Margarita Zayas (1), Peter Friebe (1), Torsten Schaller (2), Ralf Bartenschlager (1), * Nicole Appel (1) (1) University of Heidelberg, Department of Molecular Virology, Heidelberg, Germany; (2) University College London, Department of Infection and Immunity, London, United Kingdom |
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| Importance of HCV p7-protein for Efficient Assembly and Release of Infectious Virions * Christiane Brohm (1), Eike Steinmann (1), Sibylle Haid (2), Stephanie Kallis (1), Francois Penin (3), Ralf Bartenschlager (1), Thomas Pietschmann (2) (1) University Heidelberg, Molecular Virology, Heidelberg, Germany; (2) Twincore center, Experimental Virology, Hannover, Germany; (3) Institute of Biology and Chemistry of Proteins, Lyon, France |
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| The hepatitis C virus IRES-mediated translation is modulated by both cis and trans viral factors * Sofia Lourenço (1), Fleur Costa (1), Béatrice Desbarges (1), Annie Cahour (1) (1) Laboratoire de Virologie CERVI, GH Pitié Salpêtrière, Paris, FRANCE |
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| Hepatitis C virus replication involves nuclear proteins Olaf Isken (1), Martina Baroth (1), Susan Weinlich (2), Dirk Ostareck (2), Antje Ostareck (2), * Sven-Erik Behrens (2) (1) Fox Chase Cancer Center, Philadelphia, USA; (2) Martin-Luther-University Halle-Wittenberg, Institute of Biochemistry/Biotechnology, Halle, Germany |
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| Motility of Small Hepatitis C Virus Replication Complexes * Benno Wölk (1), Darius Moradpour (2), Charles M. Rice (3) (1) Hannover Medical School, Virology, Hannover, Germany; (2) Centre Hospitalier Universitaire Vaudois, Division of Hepatology, Lausanne, Switzerland; (3) The Rockefeller University, Center for the Study of Hepatitis C, New York, USA |
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13.00 - 14.00 h |
BREAK |
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| 14.00 – 16.00 h / Room Tokio Symposium III Emerging Viruses |
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| Chair: | Hans-Dieter Klenk, Thomas C. Mettenleiter |
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| 14.00 - 14.15 h | Poster Prizes Presenter: Ulrich Schubert |
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| Keynote Lecture: 14.15 - 14.45 h |
Paul Sharp: The origins of AIDS |
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| 14.45 - 15.15 h Introduction: Award Lecture: |
Heine-Medin Award: Marion Koopmans Lia van der Hoek: Human coronaviruses, what's new? |
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| 15.15 - 15.45 h Introduction: Awardee |
Gardner Lecture: Annika Linde Ralf Bartenschlager: Lessons learnt from hepatitis C virus cell culture systems: Insights into basic virology and clinical implications |
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| 15.45 - 16.00 h | Farewell Otto Haller, Bernhard Fleckenstein |
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